From the beginning we have been involved in several Drug Discovery projects for pharmaceutical companies, with whom we have worked side by side in order to prepare new compounds for the screening cascade.

We contribute with innovation, productivity, communication and flexibility: the aim is prepare the maximum number of different compounds in the least possible time.

The work methodology that we follow in these projects involves starting from a given lead, supplied by the client, which we use to develop, design, evaluate and test new routes for synthesis that allow to reach the proposed goals. We synthetize as needed the required scaffolds and building blocks, and we make heavy use of paralell and microwave techniques. The usual requirements for this type of work are commonly quantities up to 100 mg and purities greater than 95% (HPLC-MS). Each compound that we supply is supported by the necessary analytical documentation (typically 1H-NMR and HPLC-MS) to guarantee the identity and purity.

Most relevant points in a research project:

Design and assesment of new routes

Heavy use of parallelization and microwave

Preparation of scaffolds and building blocks ad hoc

Preparation of focused libraries

Preparation of additional product batches (multigram)

Rigurous quality control(Certificate of Analysis for each compound)

Appointment of an expert, dedicated project manager

Weekly reports (by e-mail)

Encrypted electronic documents transmission (with PGP by e-mail)

Monthly teleconferences (or more frequently if requested)

Complete confidentiality

Detailed Final Report of the project

IP belongs to client from beginning to end