Papers & Patents

Find here some papers and patents derived from the results obtained in client sponsored projects or in our own R&D projects.

• Selective copper-promoted cross-coupling reaction of anilines and alkylboranes, Tetrahedron Lett. 2012, 53(7): 769-772

• ES 2353297 (B1) - Procedimiento para la preparacion de N-(1-feniletil)anilinas, sales, y solvatos de las mismas utiles como antagonistas de 5-HT6 de serotonina.

• WO 2011051452 (A1) - N-containing heteroaryl derivatives as JAK3 kinase inhibitors.

• WO 2009115393 (A1) - Process for the preparation of N-(phenylethyl) anilines salts and solvates thereof useful as serotonin 5-HT6 antagonists.

• US 7879912 (B2) Process for preparing 3,3-diarylpropylamines.

• Selective Monomethylation of Anilines by Cu(OAc)2-Promoted Cross-Coupling with MeB(OH)2, Org. Lett. 2009, 11(8): 1677-1680

• Selective Copper-Promoted Cross-Coupling of Aromatic Amines with Alkyl Boronic Acids, Synlett 2010(14): 2101-2105

• Microwave-assisted aza-Cope rearrangement of N-allylanilines, Tetrahedron Lett. 2008, 49(12), 2002-2004

• Discovery and Characterization of 4’-(2-Furyl)-N-pyridin-3-yl-4,5’-bipyrimidin-2’-amine (LAS38096), a Potent, Selective, and Efficacious A2B Adenosine Receptor Antagonist, J. Med. Chem., 2007, 50 (11), pp 2732–2736