Custom Synthesis

Do you need a compound that isn’t commercially available? A reference compound needed in your cGMP process? A small quantity of a standard used for pharmacological screening? We can offer you these and more.

We can provide you with synthetic procedures, reproduce published methods, or design and test new routes for your compounds.

Our team offers special expertise in the following fields:

• Heterocyclic chemistry
• Multi-step synthesis
• Microwave parallel synthesis
• Parallel synthesis
• Synthesis of small functionalised molecules
• Synthesis of small focused libraries
• Synthesis of building blocks
• Synthesis of process impurities
• Photochemistry
• Enzymatic reactions

Our portfolio of reactions includes, but is not limited to:

• Suzuki reaction
• Buchwald reaction
• Heck reaction
• Sonogashira reaction
• Kumada reaction
• Negishi coupling
• Stille reaction
• Reductive amination
• Enzymatic resolutions
• Acylations
• Alkylations
• Esterifications
• Nucleophilic substitutions
• Reductions and oxidations
• Iodination and bromination
• Friedel-Crafts alkylation / acylation
• Grignard reaction
• Organolithium reagents
• High-pressure hydrogenations
• Wittig and Horner-Emmons
• Bischler-Napieralski reaction

Each product is supported by full analytic documentation and MSDS. And if you need both the compound and the synthetic method, we can supply you with a reproducible, well-documented process.

If you’re looking for a GMP impurities supplier, pharmacological standards, advanced synthesis intermediates, building blocks, or any other chemical substance, we can help. It’s our thing.

These case studies offer just a few of the many examples of how we have synthesized custom material to help our clients.