| Top Five |
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| Shake Well Before Use |
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| Easy and wet protocol for the Negishi reaction. |
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| More info |
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| Greenhouse Effect |
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| A carbonylation reaction which uses CO2. |
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| More info |
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| Umpolung |
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| An inverted alternative to the usual Buchwald-Hartwig amination. |
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| More info |
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| Bone Dry |
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| Selective method for the anhydrous hydrolysis of nitriles. |
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| More info |
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| On Phenols |
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| Four papers using phenols as starting materials for organometallics couplings. |
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| More info |
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| Interesting times |
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| An ancient chinese curse says that "May you live in interesting times". This crisis is an interesting time indeed, but you can extract some lessons for this hard time. One of this lessons was suggested to me by a commercial on TV.
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| Read more... |
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| Review of the month : Coupling of Heteroarene C-H bonds |
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| In several issues of this newsletter we have included several papers on the topic of the C-H direct functionalization. There has been an increasing interest in this field and the number of papers published grows each month. Bellina and Rossi have just published a review covering the recent advances in the functionalization of heteroarene C-H bonds with aryl halides, pseudohalides, trifluoroborates and iodonium salts. A quick way for medicinal chemists to keep in touch with this topic. |
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| Read more... |
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| Our services : HPLC Services |
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| GalChimia is known by his services in the field of Synthetic Organic Chemistry, but that work relies also on an efficient, well equiped analytical department supporting the chemists in the lab. We extend that support to our clients providing them with a broad array of HPLC techniques, including chiral and preparative LC. See here more information about our capabilities on analytical and preparative HPLC.
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