Papers&Reviews

A selective sulfamoylation agent
A selective sulfamoylation agent
May 25, 2021

Check our latest article about the preparation of primary sulfamates and sulfamides from the corresponding alcohols and amines.

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Magic methyl nowadays
Magic methyl nowadays
April 9, 2021

This review from ChemSocRev by Dixon, Leight et al. covers the different methods currently available for the methylation of sp2 and sp3 C-H positions.

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Autocatalytic photoredox Chan–Lam
Autocatalytic photoredox Chan–Lam
March 16, 2021

This paper by Kozlowski and Jia uses a modern approach: a copper-catalyzed photoredox dehydrogenative Chan–Lam reaction

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GalChimia_plantillas_GalChimia
One-pot access to primary sulfonamides
February 10, 2021

The sulfonamide group is one of those chemical moieties that have been around for a long time, but their preparation is not always trivial.

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GalChimia-aminopyridines-destacada
Easy Access to 2-Aminopyridines
December 4, 2020

This paper describes the development of a novel reagent for the selective amination of pyridines at the C2 position, a work by Fier et al.

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anilines
A Different Approach to Anilines
November 24, 2020

Earlier this year, Leonori et al. reported a novel and ingenious approach for the synthesis of anilines. Click here to read the full article!

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one way or another
One Way or Another
October 29, 2020

Today we talk about this work by Cavallo and Rueping, which describes the regioselective cleavage of epoxides and oxetanes.

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The Options Out There
The Options Out There
October 5, 2020

We feature an article from ACS Med Chem Lett. where seven different C(sp2)–C(sp3) cross-coupling methodologies are compared for highly functionalized substrates.

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Standing on the shoulders of giants
Standing on the Shoulders of Giants
August 5, 2020

Wei et al. have come up with a new method than can replace aliphatic amino groups with difluoromethyl groups in a rather straightforward manner.

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Julia in July
Julia in July
July 29, 2020

Julia is one of the most widely used reactions in organic synthesis. This is a new reagent for the Julia-Kocienski reaction, a modification of the original Julia reaction.

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