Papers&Reviews

Another one from Japan
May 1, 2008

Copper-Mediated Direct Arylation of Benzoazoles with Aryl Iodides From the Far East, here comes another interesting paper about C–H functionalization, in…

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Room temperature is better
May 1, 2008

Room-Temperature and Phosphine-Free Palladium-Catalyzed Direct C-2 Arylation of Indoles Direct C–H functionalization is an attractive way to increase molecular diversity. A…

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Old rockers never die
March 1, 2008

A Simple and Convenient One-pot Method for the Preparation of Heteroaryl-2-imidazoles from Nitriles Some chemists say that old chemistry is the…

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Brevity is the soul of wit
March 1, 2008

Concise Synthesis of 2-Amino-4(3H)-quinazolinones from Simple (Hetero)aromatic Amines Short methods for the preparation of nitrogen heterocycles are always welcome. In this…

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What the Heck
March 1, 2008

Oxygen and Base-Free Oxidative Heck Reactions of Arylboronic Acids with Olefins The Heck reaction has been around for more than 25…

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One step beyond reductive amination
March 1, 2008

Scope of Aminomethylations via Suzuki–Miyaura Cross-Coupling of Organotrifluoroborates Once again, the development of an organometallic cross-coupling reaction increases the array of…

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Buy one, get one free
March 1, 2008

A New Paradigm for Carbon–Carbon Bond Formation: Aerobic, Copper-Templated Cross-Coupling We are used to carry out reactions to yield a product….

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New bases for DoM
January 1, 2008

Direct ortho-Cupration: A New Route to Regioselectively Functionalized Aromatics When talking about directed ortho-metallation (DoM), most people think about organolithium bases,…

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Triazoles through ruthenium
January 1, 2008

Ruthenium-Catalyzed Cycloaddition of Aryl Azides and Alkynes The use of a Ru catalyst allows now the preparation of 1,5-disubstituted triazoles under…

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Halogenating the gap
January 1, 2008

Meta-Halogenation of 1,3-Disubstituted Arenes via Iridium-Catalyzed Arene Borylation Preparation of aryl halides is a key step in many syntheses, but the…

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