Papers & Reviews

Monofluorination for You
April 15, 2015

Monofluorination of Organic Compounds: 10 Years of Innovation This is one review that you must read or you MUST read if…

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April 1, 2015

Transition-Metal-Free Hydration of Nitriles Using Potassium tert-Butoxide under Anhydrous Conditions A simple, controlled hydrolisis of nitriles using potassium tert-butoxide. This is…

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Ringing All the Way
March 26, 2015

Palladium-Catalyzed, Ring-Forming Aromatic C–H Alkylations with Unactivated Alkyl Halides Formation of carbocycles and saturated heterocycles through a palladium mediated intramolecular radical…

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We Love Pyrazoles
March 24, 2015

Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis A method for the synthesis of 1,4-disubstituted pyrazoles using ruthenium-catalyzed hydrogen transfer….

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Tosylates to the Rescue
March 16, 2015

Engaging Nonaromatic, Heterocyclic Tosylates in Reductive Cross-Coupling with Aryl and Heteroaryl Bromides Reductive coupling of common aliphatic heterocycles (piperidines, pyrrolidines, pyranes…

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And I Mean Everything
March 12, 2015

Palladium-Catalyzed Coupling of Azoles or Thiazoles with Aryl Thioethers via C–H/C–S Activation Coupling of azoles and thiazoles with aryl thioeters when…

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Mixing is Right
March 9, 2015

Condensed-Phase, Halogen-Bonded CF3I and C2F5I Adducts for Perfluoroalkylation Reactions An old reagent for trifluoromethylation turned user-friendly. It is a pity that…

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Sometimes It Happens
March 5, 2015

Nickel-Catalyzed Decarboxylative Cross-Coupling of Perfluorobenzoates with Aryl Halides and Sulfonates Conditions to carry out a Suzuki-like coupling with perfluorinated benzoates. I…

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Bulky Amines that Work
February 27, 2015

Rational Ligand Design for the Arylation of Hindered Primary Amines Guided by Reaction Progress Kinetic Analysis A working protocol for the…

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A New Age for Chlorination
February 20, 2015

A Practical Lewis Base Catalyzed Electrophilic Chlorination of Arenes and Heterocycles Mild chlorination method of arenes and heteroarenes. Here you have…

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