Impressive, Most Impressive
May 27, 2015Practical olefin hydroamination with nitroarenes A new, powerful method to generate quaternary amines without using expensive catalysts. Baran has done it…
Read MoreGotcha!
May 21, 2015In Situ Generation of Difluoromethyl Diazomethane for [3+2] Cycloadditions with Alkynes Safe preparation of an elusive reagent, difluoromethyl diazomethane, and its…
Read MoreWorking on the Edge
May 19, 2015Metal-Free, Regio- and Stereoselective Synthesis of Linear (E)?Allylic Compounds Using C, N, O, and S Nucleophiles Using terminal alkenes to prepare…
Read MoreSuzuki on the Rocks
May 14, 2015Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates Not only we can couple the most exotic moieties, we can do…
Read MoreCatalysis for Amides
May 4, 2015Catalytic Chemical Amide Synthesis at Room Temperature: One More Step Toward Peptide Synthesis An uncommon use of a boronic acid: as…
Read MoreMore Last-Stage Activation
April 29, 2015Manganese-Catalyzed Late-Stage Aliphatic C?H Azidation Another protocol to carry out a late-stage azidation using a Mn complex. Two months ago we…
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Monofluorination for You
April 15, 2015Monofluorination of Organic Compounds: 10 Years of Innovation This is one review that you must read or you MUST read if…
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April 1, 2015Transition-Metal-Free Hydration of Nitriles Using Potassium tert-Butoxide under Anhydrous Conditions A simple, controlled hydrolisis of nitriles using potassium tert-butoxide. This is…
Read MoreRinging All the Way
March 26, 2015Palladium-Catalyzed, Ring-Forming Aromatic C–H Alkylations with Unactivated Alkyl Halides Formation of carbocycles and saturated heterocycles through a palladium mediated intramolecular radical…
Read MoreWe Love Pyrazoles
March 24, 2015Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis A method for the synthesis of 1,4-disubstituted pyrazoles using ruthenium-catalyzed hydrogen transfer….
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