Monofluorination for You
April 15, 2015Monofluorination of Organic Compounds: 10 Years of Innovation This is one review that you must read or you MUST read if…
Read MoreOxymoron
April 1, 2015Transition-Metal-Free Hydration of Nitriles Using Potassium tert-Butoxide under Anhydrous Conditions A simple, controlled hydrolisis of nitriles using potassium tert-butoxide. This is…
Read MoreRinging All the Way
March 26, 2015Palladium-Catalyzed, Ring-Forming Aromatic C–H Alkylations with Unactivated Alkyl Halides Formation of carbocycles and saturated heterocycles through a palladium mediated intramolecular radical…
Read MoreWe Love Pyrazoles
March 24, 2015Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis A method for the synthesis of 1,4-disubstituted pyrazoles using ruthenium-catalyzed hydrogen transfer….
Read MoreTosylates to the Rescue
March 16, 2015Engaging Nonaromatic, Heterocyclic Tosylates in Reductive Cross-Coupling with Aryl and Heteroaryl Bromides Reductive coupling of common aliphatic heterocycles (piperidines, pyrrolidines, pyranes…
Read MoreAnd I Mean Everything
March 12, 2015Palladium-Catalyzed Coupling of Azoles or Thiazoles with Aryl Thioethers via C–H/C–S Activation Coupling of azoles and thiazoles with aryl thioeters when…
Read MoreMixing is Right
March 9, 2015Condensed-Phase, Halogen-Bonded CF3I and C2F5I Adducts for Perfluoroalkylation Reactions An old reagent for trifluoromethylation turned user-friendly. It is a pity that…
Read MoreSometimes It Happens
March 5, 2015Nickel-Catalyzed Decarboxylative Cross-Coupling of Perfluorobenzoates with Aryl Halides and Sulfonates Conditions to carry out a Suzuki-like coupling with perfluorinated benzoates. I…
Read MoreBulky Amines that Work
February 27, 2015Rational Ligand Design for the Arylation of Hindered Primary Amines Guided by Reaction Progress Kinetic Analysis A working protocol for the…
Read MoreA New Age for Chlorination
February 20, 2015A Practical Lewis Base Catalyzed Electrophilic Chlorination of Arenes and Heterocycles Mild chlorination method of arenes and heteroarenes. Here you have…
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