OxymoronApril 1, 2015
Transition-Metal-Free Hydration of Nitriles Using Potassium tert-Butoxide under Anhydrous Conditions A simple, controlled hydrolisis of nitriles using potassium tert-butoxide. This is…
Ringing All the WayMarch 26, 2015
Palladium-Catalyzed, Ring-Forming Aromatic C–H Alkylations with Unactivated Alkyl Halides Formation of carbocycles and saturated heterocycles through a palladium mediated intramolecular radical…
We Love PyrazolesMarch 24, 2015
Synthesis of Pyrazoles from 1,3-Diols via Hydrogen Transfer Catalysis A method for the synthesis of 1,4-disubstituted pyrazoles using ruthenium-catalyzed hydrogen transfer….
Tosylates to the RescueMarch 16, 2015
Engaging Nonaromatic, Heterocyclic Tosylates in Reductive Cross-Coupling with Aryl and Heteroaryl Bromides Reductive coupling of common aliphatic heterocycles (piperidines, pyrrolidines, pyranes…