Top Reviews

More Drugs, Please
January 21, 2016

One size does not fit all: Challenging some dogmas and taboos in drug discovery This brief review by Chai (Singapore) and…

Read More
monofluorination-for-you
Monofluorination for You
April 15, 2015

Monofluorination of Organic Compounds: 10 Years of Innovation This is one review that you must read or you MUST read if…

Read More
Review of the month: Fluorination Methods
February 16, 2015

It is curious how these things happen. These last weeks I have been checking old entries of the blog, and I…

Read More
Review of the month: spirocyclic scaffolds in drug discovery
January 23, 2015

When I was a PhD student (mid 90s), reviews were something that you could find in three or four journals: Chemical…

Read More
Review of the month: Magic Methyl
November 24, 2014

Hmmm, ok, this is not exactly the review of the month. It is more like the review of this month but…

Read More
Review of the month : Iron Catalyzed C-H Activation
November 1, 2011

C-H activation is one of the blooming fields in organocatalysis. As example, the first paper in the Top Five of this…

Read More
A Bunch of Good Reviews
September 1, 2011

How can we say? There were so many interesting reviews in August that simply we could not make our mind. So…

Read More
Review of the month : Bioisosteres in Drug Design
January 1, 2011

Bioisosteres are the daily bread for medicinal chemists, though isosterism is in fact an old concept. The title of this review…

Read More
Review of the month : 2-Iodoxybenzoic acid (IBX)
September 1, 2010

For many chemists around the IBX is just another oxidant, and one with a bad reputation. Once seen only as a…

Read More
Review of the month: Advances in Multicomponent Reactions
July 1, 2010

Multicomponent reactions (MCRs) are chemical transformations in which three or more reactants form a product derived from all of the inputs….

Read More