GA01178

Lovastatin Hydroxy Acid Sodium Salt; Lovastatin Impurity B (EP)

98%

(3R,​5R)​-​7-​[(1S,​2S,​6R,​8S,​8aR)​-​2,​6-​Dimethyl-​8-​[[(2S)​-​2-​methylbutanoyl]​oxy]​-​1,​2,​6,​7,​8,​8a-​hexahydronaphthalen-​1-​yl]​-​3,​5-​dihydroxyheptanoic Acid Sodium Salt

  • CAS RN: 75225-50-2
  • Mol Formula: C24H37NaO6
  • Mol Weight: 444.55

Others quantities on request

  • More Information

    GA01178

    Lovastatin is a statin drug, used for lowering cholesterol in those with hypercholesterolemia to reduce risk of cardiovascular disease. It is a naturally occurring compound found in food such as oyster mushrooms or red yeast rice. Lovastatin is a prodrug, an inactive lactone in its native form, the gamma-lactone closed ring form in which it is administered, is hydrolysed in vivo to the β-hydroxy acid open ring form; which is the active form. As all statins, it acts by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase.

    We have successfully synthesized impurities of the Lovastatin. This will be of interest to pharmaceutical companies and analytical labs.