New papers Archives

Three tough atoms

febrero 14, 2020

Difluoromethylation of Phenols and Thiophenols with S-(Difluoromethyl)sulfonium Salt: Reaction, Scope and Mechanistic Study.

Another long distance call

enero 13, 2020

Introduction of a CF2H moiety in benzylic positions using a copper catalyst.

The Less Smelly Way

diciembre 2, 2019

This paper came to our attention thanks to one of our Project Managers, always watching for new useful reactions. Check it out now!

Long distance call

noviembre 6, 2019

In this paper, we will see the synthesis of piperidines using a remote d C–H functionalization of amines with a chiral copper catalyst.

Catalytic Mitsunobu: The face-lift of a workhorse

octubre 21, 2019

This work tackles, once again, one of the most used methods to carry out the nucleophilic substitution of alcohols in one step, the Mitsunobu reaction.

Flowing into indoles

septiembre 5, 2019

An interesting application of flow chemistry for the continuous synthesis of #indoles through the palladium-catalyzed deoxygenation of nitrostilbenes with CO as the reducing agent.

Review of the Month: Opportunities with Macrocycles

junio 26, 2019

The macrocycles provides access to new chemical space and opportunities in drug discovery that are otherwise difficult to reach with small molecules.

Re-energizing the Birch reduction

mayo 9, 2019

Phil S. Baran and his co-workers had made a reality above chemical dreams by the application of Li-ion battery chemistry in synthetic organic electroreduction.

(Un)touchable

mayo 25, 2016

Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes for Diverse C–F Bond Functionalizations Using a mixed catalytic system to promote the transformation of aromatic fluorides…

Printing Your Catalyst

mayo 6, 2016

3D printing of a heterogeneous copper-based catalyst The impact of some technologies like 3D printing is remarkable. In this case, it…