Flowing into indoles
septiembre 5, 2019An interesting application of flow chemistry for the continuous synthesis of #indoles through the palladium-catalyzed deoxygenation of nitrostilbenes with CO as the reducing agent.
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Re-energizing the Birch reduction
mayo 9, 2019Phil S. Baran and his co-workers had made a reality above chemical dreams by the application of Li-ion battery chemistry in synthetic organic electroreduction.
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(Un)touchable
mayo 25, 2016Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes for Diverse C–F Bond Functionalizations Using a mixed catalytic system to promote the transformation of aromatic fluorides…
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Printing Your Catalyst
mayo 6, 20163D printing of a heterogeneous copper-based catalyst The impact of some technologies like 3D printing is remarkable. In this case, it…
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Activated
enero 25, 2016A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents Activated esters of alkylic acids as building blocks for the…
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More Drugs, Please
enero 21, 2016One size does not fit all: Challenging some dogmas and taboos in drug discovery This brief review by Chai (Singapore) and…
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Monofluorination for You
abril 15, 2015Monofluorination of Organic Compounds: 10 Years of Innovation This is one review that you must read or you MUST read if…
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Review of the month: Fluorination Methods
febrero 16, 2015It is curious how these things happen. These last weeks I have been checking old entries of the blog, and I…
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