GalChimia cuenta con proyectos de I+D propios, enfocados a la preparación de compuestos químicos novedosos. Así, conseguimos aplicar nuestro conocimiento químico a campos en los que normalmente no trabajamos, como estructura supramoleculares, nanomateriales y otros.
Publicaciones
- Optimisation of a key cross-coupling reaction towards the synthesis of a promising antileishmanial compound. Tetrahedon Lett. 2019, 60(18), 1243–1248.
- A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity. J. Med. Chem., 2017, 60 (23), 9575–9584.
- Selective copper-promoted cross-coupling reaction of anilines and alkylboranes, Tetrahedron Lett. 2012, 53(7), 769–772.
- Design of Experiments has far wider use than simply optimising yields, Speciality Chemicals Magazine 2011, 3, 18–19.
- Selective Monomethylation of Anilines by Cu(OAc)2-Promoted Cross-Coupling with MeB(OH)2, Org. Lett. 2009, 11(8), 1677–1680.
- Selective Copper-Promoted Cross-Coupling of Aromatic Amines with Alkyl Boronic Acids, Synlett 2010(14), 2101–2105.
- Microwave-assisted aza-Cope rearrangement of N-allylanilines, Tetrahedron Lett. 2008, 49(12), 2002–2004.
Carteles y libros blancos
Design and Synthesis of linkers for Glycan-Coated Gold Nanoparticles Used in Drug Discovery
Pampín, B.; Codesido, E.; Masse, J.; Cruces, J.
Design and Synthesis of a Library of Chromogenic Chemical Entities for the Discovery of New Thermostable Enzymes Relevant for the Chemical Industry
Begoña Pampín Casal, Jacobo Cruces Colado, Julie Masse, María Luisa Rúa Rodríguez, María Isabel González Siso
Patentes
- WO 2016078770 (A1) – Preparation of spiro-isoquinoline-1,4′-piperidine compounds having multimodal activity against pain
- WO 2014177517 (A1) – Preparation process of an agonist of the thrombopoietin receptor
- WO 2011147910 (A1) – Pyrazole compounds as sigma receptor inhibitors
- WO 2011051452 (A1) – N-Containing heteroaryl derivates as JAK3 kinase inhibitors
- WO 2009115393 (A1) – Process for the preparation of N-(Phenilethyl) Anilines salts an solvates thereof useful as serotonin 5-HT6 antagonists
- US 7879912 (B2) Process for preparing 3,3-Diarylpropylamines