More Drugs, Please

Drug Discovery

PyFluor – OH Replacement Service

Fluorination

Late-stage functionalization

PyFluor

Multimetals for Biaryls

Biaryl

Couplings

Nickel

Palladium

Triflates

Zinc

Finally!

Buchwald

C-X bond formation

Fluorination

Palladium

Triflates

An Old Reaction Revisited

Med Chem

Reductive Amination

Silanes

Not So Easy

Heterocycles

Med Chem

Metallation

Sulfonates

TCPC

Zincates

New CO-nditions

Amides

Carbonylation

Catalysis

Med Chem

Palladium

Tosylates

Bubbles

Carbon Monoxide

Carbonylation

Couplings

Med Chem

Ipso Facto

Borylation

C-O breakup

Ethers

Halogenation

Nickel

Impressive, Most Impressive

Alkenes

Amines

Anilines

Catalysis

Heterocycles

Iron

Med Chem

Nitrocompounds

Gotcha!

Cycloadditions

Fluorination

Heterocycles

Med Chem

Pyrazoles

Working on the Edge

Allylic compounds

Bromination

Med Chem

Nucleophiles

Nucleophilic Substitution