New Papers

mitsunobo reaction
Catalytic Mitsunobu: The face-lift of a workhorse
Outubro 21, 2019

This work tackles, once again, one of the most used methods to carry out the nucleophilic substitution of alcohols in one step, the Mitsunobu reaction.

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Flowing into indoles
Flowing into indoles
Setembro 5, 2019

An interesting application of flow chemistry for the continuous synthesis of #indoles through the palladium-catalyzed deoxygenation of nitrostilbenes with CO as the reducing agent.

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Birch reduction
Re-energizing the Birch reduction
Maio 9, 2019

Phil S. Baran and his co-workers had made a reality above chemical dreams by the application of Li-ion battery chemistry in synthetic organic electroreduction.

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Activated
Maio 25, 2016

A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents Activated esters of alkylic acids as building blocks for the…

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Printing Your Catalyst
Maio 6, 2016

3D printing of a heterogeneous copper-based catalyst The impact of some technologies like 3D printing is remarkable. In this case, it…

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(Un)touchable
Xaneiro 25, 2016

Ni/Cu-Catalyzed Defluoroborylation of Fluoroarenes for Diverse C–F Bond Functionalizations Using a mixed catalytic system to promote the transformation of aromatic fluorides…

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More Drugs, Please
Xaneiro 21, 2016

One size does not fit all: Challenging some dogmas and taboos in drug discovery This brief review by Chai (Singapore) and…

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Monofluorination for You
Abril 15, 2015

Monofluorination of Organic Compounds: 10 Years of Innovation This is one review that you must read or you MUST read if…

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Review of the month: Fluorination Methods
Febreiro 16, 2015

It is curious how these things happen. These last weeks I have been checking old entries of the blog, and I…

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