Top Reviews

More Drugs, Please
Xaneiro 21, 2016

One size does not fit all: Challenging some dogmas and taboos in drug discovery This brief review by Chai (Singapore) and…

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Monofluorination for You
Abril 15, 2015

Monofluorination of Organic Compounds: 10 Years of Innovation This is one review that you must read or you MUST read if…

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Review of the month: Fluorination Methods
Febreiro 16, 2015

It is curious how these things happen. These last weeks I have been checking old entries of the blog, and I…

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Review of the month: spirocyclic scaffolds in drug discovery
Xaneiro 23, 2015

When I was a PhD student (mid 90s), reviews were something that you could find in three or four journals: Chemical…

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Review of the month: Magic Methyl
Novembro 24, 2014

Hmmm, ok, this is not exactly the review of the month. It is more like the review of this month but…

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Review of the month : Iron Catalyzed C-H Activation
Novembro 1, 2011

C-H activation is one of the blooming fields in organocatalysis. As example, the first paper in the Top Five of this…

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A Bunch of Good Reviews
Setembro 1, 2011

How can we say? There were so many interesting reviews in August that simply we could not make our mind. So…

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Review of the month : Bioisosteres in Drug Design
Xaneiro 1, 2011

Bioisosteres are the daily bread for medicinal chemists, though isosterism is in fact an old concept. The title of this review…

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Review of the month : 2-Iodoxybenzoic acid (IBX)
Setembro 1, 2010

For many chemists around the IBX is just another oxidant, and one with a bad reputation. Once seen only as a…

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Review of the month: Advances in Multicomponent Reactions
Xullo 1, 2010

Multicomponent reactions (MCRs) are chemical transformations in which three or more reactants form a product derived from all of the inputs….

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