Saving Steps

Amidation

Couplings

Med Chem

Palladium

And Now, the Other Way

Copper

Couplings

Hydroxylation

Med Chem

Phenols

You See It, You Don’t

C-C bond formation

C-H activation

Med Chem

Phenols

Silanol

CN Without CN

Cyanation

Indoles

OH! F?

C-X bond formation

Fluorination

Med Chem

Phenols

A Bunch of Good Reviews

H4 Receptor

Magic Methyl

Prostanoid Receptors

Pyrazoles

Tetrahydroquinolines

An Old Story

Med Chem

Microwaves

Reductive Amination

Agatha Christie’s Tribute

Cyanation

Med Chem

Nitriles

Palladium

Potassium Ferrocyanide

Zinc Cyanide

Even easier

Carbonylation

Heck

Med Chem

Microwaves

Palladium

Weinreb Amides

Counterintuitive

C-X bond formation

Med Chem

Pyridines

Sulfonylation

Incredible but True

C-X bond formation

Couplings

Nucleophilic Substitution

Palladium

Ullmann

Have You Seen an Oxygen?

Alkyl Ethers

Couplings

Deoxygenation

Grignard

Nickel