GA01165

Lovastatin Impurity C (EP)

98%

(2S)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-8-[2-[(2R)-3,6-Dihydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl Ester

  • CAS RN: 109273-98-5
  • Mol Formula: C24H34O4
  • Mol Weight: 386.52

Others quantities on request

  • More Information

    GA01165

    Lovastatin is a statin drug, used for lowering cholesterol in those with hypercholesterolemia to reduce risk of cardiovascular disease. It is a naturally occurring compound found in food such as oyster mushrooms or red yeast rice. Lovastatin is a prodrug, an inactive lactone in its native form, the gamma-lactone closed ring form in which it is administered, is hydrolysed in vivo to the β-hydroxy acid open ring form; which is the active form. As all statins, it acts by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase.

    We have successfully synthesized impurities of the Lovastatin. This will be of interest to pharmaceutical companies and analytical labs.