Referente europeo en síntese química, aportando solucións innovadoras para o descubrimento de fármacos

Meet us at the flagship event of the EFMC, the International Symposium on Medicinal Chemistry, which is taking place in Nice (France) on September 4-8, 2022.

Our latest article reports the high termal activity and stability of enzyme KLEST-3S in aqueous and organic media in key reactions with commercial substrates.

Our latest article has just been published in the Journal of Medicinal Chemistry, describing the discovery of an allosteric modulator of GLP-1R as part of the project HUMANFARMA.

Our annual exercise of transparency. Read on about our good chemistry and how we performed in 2021.

GalChimia ha recibido el Premio Galicia Innovación 2021 de la Xunta de Galicia en la categoría de Pequeña y Mediana Empresa.

La formación es una de las bases de nuestro desarrollo y trabajamos para impulsar la vocación científica entre los más jóvenes.

The 2021 Chemistry Nobel Prize has been awarded to Benjamin List and David MacMillan “for the development of asymmetric organocatalysis”.

Here is our tribute to Emmanuelle Charpentier and Jennifer Doudna for their pioneering work in gene editing and the preceding discoveries that made possible the development of CRISPR technology

According to the ASEBIO 2019 report, Spain remains a powerful region in terms of biotechnology and Research & Development efforts.

In GalChimia, as part of the MedChem community, we feel this could be a good time to reflect and share some thoughts about the COVID-19 situation.

Gaich et al. have recently reported the total synthesis of an extremely complicated molecule, canataxpropellane. We thus wonder, have we reached the limits of synthetic complexity?

It’s time to talk about the chemical elements that fill the periodic table. Have you ever wondered why we have so many (or so few) elements? Keep reading!

Check our latest article about the preparation of primary sulfamates and sulfamides from the corresponding alcohols and amines.

This review from ChemSocRev by Dixon, Leight et al. covers the different methods currently available for the methylation of sp2 and sp3 C-H positions.

This paper by Kozlowski and Jia uses a modern approach: a copper-catalyzed photoredox dehydrogenative Chan–Lam reaction

The sulfonamide group is one of those chemical moieties that have been around for a long time, but their preparation is not always trivial.

This paper describes the development of a novel reagent for the selective amination of pyridines at the C2 position, a work by Fier et al.

Earlier this year, Leonori et al. reported a novel and ingenious approach for the synthesis of anilines. Click here to read the full article!