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Modular factories for the production of 100 compounds from the SHIKIMATE pathway

R&D Project SHIKIFACTORY100

A collaborative effort to boost EU synthetic biology competitiveness

The ShikiFactory100 Horizon2020 project gathers 11 partners from 7 countries: SilicoLife (Portugal), Technical University of Denmark, European Molecular Biology Laboratory (Germany), École Polytechnique Fédérale de Lausanne (Switzerland), NOVA University of Lisbon (Portugal), University of Manchester (UK), University of Minho (Portugal), c-LEcta (Germany), GalChimia (Spain), NNFCC (UK), and DSM (The Netherlands).

The project will provide economically feasible and sustainable biotechnological processes as alternatives to oil-based chemistry. The global chemical industry has initiated a crucial transition from petrochemical processes to bio-based chemical processes. The ShikiFactory100 project aims toward the production of a pool of more than 100 high-value compounds from the shikimate pathway, a hub in cell metabolism, through the development of an optimized chassis and the proposal and implementation of novel biosynthetic routes for the production of known and new molecules.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement number 814408.

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