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Ultrahigh-throughput platform for the screening of thermostable proteins

R&D Project HOTDROPS

Ultrahigh-throughput platform for the screening of thermostable proteins by thermophilic in vitro transcription-translation and microfluidics

GalChimia, Novozyme, Biochemize, Drop-Tech and four Academic groups participate in the research project HotDrops, whose goal is to develop a new ultrahigh-throughput platform to search for new biocatalysts, with which large enzyme-variant libraries that were previously challenging to handle can be screened. Single bacterial cells or in-vitro transcription/translation systems can be compartmentalized into droplets, each expressing a different gene library variant. This project combines three sciences: enzymology, microfluid technology, and organic chemistry. The project has been funded by the European Union through the Seventh Framework Programme (FP7). Click here for more info

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