Catalysis

Flowing into indoles
Flowing into indoles
September 5, 2019

An interesting application of flow chemistry for the continuous synthesis of #indoles through the palladium-catalyzed deoxygenation of nitrostilbenes with CO as the reducing agent.

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Printing Your Catalyst
May 6, 2016

3D printing of a heterogeneous copper-based catalyst The impact of some technologies like 3D printing is remarkable. In this case, it…

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New CO-nditions
June 10, 2015

Aminocarbonylation of Aryl Tosylates to Carboxamides Generation of aromatic amides using CO, amines and aryl tosylates as coupling substrates. This is…

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Impressive, Most Impressive
May 27, 2015

Practical olefin hydroamination with nitroarenes A new, powerful method to generate quaternary amines without using expensive catalysts. Baran has done it…

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Catalysis for Amides
May 4, 2015

Catalytic Chemical Amide Synthesis at Room Temperature: One More Step Toward Peptide Synthesis An uncommon use of a boronic acid: as…

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More Last-Stage Activation
April 29, 2015

Manganese-Catalyzed Late-Stage Aliphatic C?H Azidation Another protocol to carry out a late-stage azidation using a Mn complex. Two months ago we…

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Earth-Abundant Catalyst
February 18, 2015

Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst C-H activation using a catalyst that is not based…

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Review of the month: Fluorination Methods
February 16, 2015

It is curious how these things happen. These last weeks I have been checking old entries of the blog, and I…

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The Final Step
February 9, 2015

Metal-Catalyzed Azidation of Tertiary C–H Bonds Suitable for Late-Stage Functionalization Another entry in the wonderful world of the C-H activation, this…

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A New Way to Amines
October 16, 2014

Direct Catalytic N?Alkylation of Amines with Carboxylic Acids Ask a medicinal chemist how many times he/she used the reductive amination. The…

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