Palladium

Flowing into indoles
Flowing into indoles
September 5, 2019

An interesting application of flow chemistry for the continuous synthesis of #indoles through the palladium-catalyzed deoxygenation of nitrostilbenes with CO as the reducing agent.

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Multimetals for Biaryls
October 23, 2015

Multimetallic catalysed cross-coupling of aryl bromides with aryl triflates A catalytic system using two metals allows the synthesis of biaryl products…

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monofluorination-for-you
Finally!
October 9, 2015

A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides The development of a new phosphine ligand…

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New CO-nditions
June 10, 2015

Aminocarbonylation of Aryl Tosylates to Carboxamides Generation of aromatic amides using CO, amines and aryl tosylates as coupling substrates. This is…

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Suzuki on the Rocks
May 14, 2015

Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates Not only we can couple the most exotic moieties, we can do…

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Ringing All the Way
March 26, 2015

Palladium-Catalyzed, Ring-Forming Aromatic C–H Alkylations with Unactivated Alkyl Halides Formation of carbocycles and saturated heterocycles through a palladium mediated intramolecular radical…

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And I Mean Everything
March 12, 2015

Palladium-Catalyzed Coupling of Azoles or Thiazoles with Aryl Thioethers via C–H/C–S Activation Coupling of azoles and thiazoles with aryl thioeters when…

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Bulky Amines that Work
February 27, 2015

Rational Ligand Design for the Arylation of Hindered Primary Amines Guided by Reaction Progress Kinetic Analysis A working protocol for the…

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Not a Poison Anymore?
February 10, 2015

Synthesis of diaryl thioethers from aryl halides and potassium thiocyanate A method for the preparation of thioethers using a Palladium catalyst…

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Anti-Atom Economy
January 30, 2015

Two-Step Cyanomethylation Protocol: Convenient Access to Functionalized Aryl- and Heteroarylacetonitriles Accesing (hetero)arylacetonitriles using no cyanide at all. If you search through…

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