Reductive Amination

An Old Reaction Revisited
June 30, 2015

Chemoselective Reductive Amination of Carbonyl Compounds for the Synthesis of Tertiary Amines Using SnCl2·2H2O/PMHS/MeOH A new protocol for a reductive amination…

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A New Way to Amines
October 16, 2014

Direct Catalytic N?Alkylation of Amines with Carboxylic Acids Ask a medicinal chemist how many times he/she used the reductive amination. The…

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An Old Story
September 1, 2011

Microwave-accelerated reductive amination between ketones and ammonium acetate Reductive amination under microwave irradiation conditions. Reductive Amination is probably one of the…

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Umpolung
January 1, 2010

Umpolung Amination: Nickel-Catalyzed Coupling Reactions of N,N-Dialkyl-N-chloroamines with Diorganozinc Reagents An inverted alternative to the usual Buchwald–Hartwig amination. There are two…

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A good alternative
March 1, 2009

Ruthenium-Catalyzed N-Alkylation of Amines and Sulfonamides Using Borrowing Hydrogen Methodology A powerful alternative to reductive amination using alcohols and a ruthenium…

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In-teresting
November 1, 2008

Highly Chemoselective Reductive Amination of Carbonyl Compounds Promoted by InCl3/Et3SiH/MeOH System A new procedure for reductive amination in protic solvents. As…

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One step beyond reductive amination
March 1, 2008

Scope of Aminomethylations via Suzuki–Miyaura Cross-Coupling of Organotrifluoroborates Once again, the development of an organometallic cross-coupling reaction increases the array of…

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