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The Less Smelly Way
December 2, 2019This paper came to our attention thanks to one of our Project Managers, always watching for new useful reactions. Check it out now!
Read MoreMixing is Right
March 9, 2015Condensed-Phase, Halogen-Bonded CF3I and C2F5I Adducts for Perfluoroalkylation Reactions An old reagent for trifluoromethylation turned user-friendly. It is a pity that…
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Review of the month: Fluorination Methods
February 16, 2015It is curious how these things happen. These last weeks I have been checking old entries of the blog, and I…
Read MoreNew Section?
December 1, 2011Synthesis of 2-(Trifluoromethyl)oxazoles from ß-Monosubstituted Enamines via PhI(OCOCF3)2-Mediated Trifluoroacetoxylation and Cyclization Synthesis of trifluoromethylated oxazoles from enamines and PIFA. If this…
Read MoreWhat you Missed Last Month
December 1, 2011What can we say? CPhI is really important and we had some very important activities going on, such as preparing the…
Read MoreAnd More CF3
October 1, 2011Silver-Mediated Trifluoromethylation of Arenes Using TMSCF3 Introduction of the trifluoromethyl moiety into aromatic rings. And now by Sanford et al. (University…
Read MoreAllylic CF3
October 1, 2011Copper-Catalyzed C(sp3)–C(sp3) Bond Formation Using a Hypervalent Iodine Reagent: An Efficient Allylic Trifluoromethylation Introduction of the trifluoromethyl moiety in allylic positions….
Read MoreHeterocyclic CF3
October 1, 2011Innate C-H trifluoromethylation of heterocycles Introduction of the trifluoromethyl moiety into heterocycles. I admit that I almost missed this paper. Honestly,…
Read MoreThe Smelly Way
April 1, 2010From Carboxylic Acids to the Trifluoromethyl Group Using BrF3 A method to convert carboxylic acids into trifluoromethyl groups. This paper by…
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